Do I have to go off of antidepressants to receive ketamine treatments?

Treatment with ketamine does not require tapering or discontinuing antidepressant medications such as SSRIs because it works through a different mechanism in the brain. Ketamine does have some interactions with medications, including benzodiazepines, and some substances, that are not a contraindication to ketamine therapy, but would be discussed with you as part of treatment planning.