How does Spravato® work?

Spravato^® works differently from common oral antidepressants. Rather than targeting serotonin, it targets the NMDA receptor, a part of the brain’s glutamate system involved in mood regulation and neuroplasticity. This unique mechanism can potentially lead to rapid improvement in symptoms and has been shown to be uniquely effective in individuals experiencing depressive symptoms that haven’t responded to other forms of treatment.